The Bible clearly indicates that the rise in famine, earthquakes, diseases and wars will be a significant sign of the coming Tribulation Period. This is the only time in history where ALL of these things are happening at the same time.
Matthew 24:7-11Amplified Bible (AMP)
7 For nation will rise against nation, and kingdom against kingdom, and there will be famines and earthquakes in various places. 8 But all these things are merely the beginning of birth pangs [of the intolerable anguish and the time of unprecedented trouble].
9 “Then they will hand you over to [endure] tribulation, and will put you to death, and you will be hated by all nations because of My name. 10 At that time many will be offended and repelled [by their association with Me] and will fall away [from the One whom they should trust] and will betray one another [handing over believers to their persecutors] and will hate one another. 11 Many false prophets will appear and mislead many.
Hosea 4:3 Authorized (King James) Version
3 Therefore shall the land mourn,
and every one that dwelleth therein shall languish,
with the beasts of the field,
and with the fowls of heaven;
yea, the fishes of the sea also shall be taken away.